Based on allele frequencies in the general population for the reported pathogenic variants (gnomAD v.4.1.0), followed by calculations using the Hardy-Weinberg equilibrium, it is estimated that approximately 1,000 and 2,400 individuals worldwide, respectively, are affected by ADGRV1-associated RP caused by pathogenic variants in these exons. Here, ADGRV1 is linked to retinitis pigmentosa 1.