ARAP1 rs1552224 was significantly linked to reduced GDM incidence (Allele Model A vs. C: OR = 0.624; 95% CI: 0.425-0.916; p-value = 0.016; Dominant Model AA vs. AC+CC: OR = 0.641; 95% CI: 0.429-0.959; p-value = 0.030), especially in women under 30, rs1552224 Aelle Model (A vs. C: OR = 0.490; 95% CI: 0.281-0.857; p -value = 0.012), Dominant Model (AA vs. AC + CC: OR = 0.523; 95% CI: 0.292-0.938; p -value = 0.030). Here, ARAP1 is linked to gestational diabetes.