PSMD14 is highly expressed in a variety of cancers and acts as an oncogene to promote tumor development and progression (Zhu et al., 2018); it has been suggested that PSMD14 may be involved in esophageal squamous cell carcinoma (ESCC) tumorigenesis (Ma et al., 2016; Seo et al., 2019; Lv et al., 2020). Here, PSMD14 is linked to cancer.