AKT1 and neoplasm: The in-depth exploration of traditional drugs also continues, such as the terpenoid Cantharidin (CTD), a multi-targeted anticancer agent derived from traditional Chinese medicine, which plays an important role in inhibiting tumor proliferation and metastasis, enhancing sensitivity and mitigating side effects in combination with radiotherapy by inhibiting the activity of PP1/PP2A and modulating the pathways of PI3K/AKT/mTOR and MAPK.