Besides, histone-modifiers of the KMT2 (histone-lysine N-methyltransferase 2) family are also frequently associated with the development of cancer, in particular KMT2A/MML1 (mixed lineage leukemia 1), which dearrangement leads to an oncogenic fusion protein in acute lymphoblastic leukemia (Ford and Dingwall, 2015). This evidence concerns the gene KMT2A and cancer.