AKT1 and neoplasm: The balance between tumor cell apoptosis and survival depends on the activities of anti-apoptotic proteins Bcl-2, Wnt and NFκB signaling pathways, as well as the ratio between the activities of mitogen-activated protein kinase (MAPK) and phosphatidylinositol-3-kinase/protein kinase B (PI3K/Akt) signaling pathways.