ERBB2 and neoplasm: Supplementary Figures 5C, D shows Luminal cases exhibit centripetal attention patterns (model’s attention originates from edge to core), implying central tumor features may drive Luminal classification, unlike TN’s edge-dependent signatures. Discrepancies in model attention localization between CC and MLO projections for HER2+ cases (vs. TN’s consistent edge-predominant pattern) may indicate HER2 tumor heterogeneity (Supplementary Figures 5E, F).