Preliminary evaluations identified three genes with prominent functions in lung cancer immunoproteasomes, a nonclassical peptide-processing complex thought to promote differentiation and enhance antigen presentation in the context of proinflammatory cytokines (18), that hold promise as transcriptional predictors: PSME1, PSME2 and PSMB9(LMP2) (19). This evidence concerns the gene PSMB9 and lung cancer.