POU2F2 and nonpapillary renal cell carcinoma: Other TFs associated with ccRCC, such as retinoic acid receptor alpha (RARA), signal transducer and activator of transcription 3 (STAT3), nuclear factor kappa—light—chain—enhancer of activated B cells (NFκB), and POU domain class 2 transcription factor 2 (POU2F2), are also upregulated in nccRCC.