EPHA1 and nonpapillary renal cell carcinoma: Furthermore, Ghoshdastider et al. conducted a single-cell analysis of intercellular communication across various cancers, including ccRCC and pRCC, and found that MCs in ccRCC and pRCC are enriched with bone morphogenetic protein (BMP) ligands and activin A receptor (ACVR) receptors, fibroblast growth factor (FGF) signaling pathways (involving various FGF ligands and receptors), and Eph/ephrin signaling pathways through autocrine or paracrine mechanisms.