HOXC5 and nonpapillary renal cell carcinoma: Integration of scRNA-seq and scATAC-seq analyses has identified a set of TFs highly expressed and specifically enriched in ccRCC tumors, including orthopedia (OTP), ventral anterior homeobox (VENTX), homeobox C5 (HOXC5), and insulin gene enhancer binding protein 1 (ISL1).