COXFA4L2 and cancer: The fetal cluster expresses Polo—like kinase (PLK)2, cluster 1 expresses NDUFA4L2, aiding cancer cells via OXPHOS, cluster 2 expresses S100A8, linked to immune modulation, and cluster 3 expresses THBS2, with TFs CCAAT—enhancer—binding protein delta (CEBPD) and FOXO3 upregulated, associated with adipocyte differentiation and tumor promotion.