For the remaining well-performing zero-shot targets without strong correlations, feature importance analysis and relevant literature suggest that DT-GPT may capture clinically meaningful relationships, such as the ferritin-to-hemoglobin ratio and components of the Albumin-Bilirubin (ALBI) score in NSCLC patients (Supplementary Fig. 11; Supplementary Table 23)44–46. The gene discussed is ALB; the disease is non-small cell lung carcinoma.