However, given the pivotal roles of cell adhesion peptides and the basement membrane for cellular function, along with our findings in the paediatric tumour ECM-associated genes (Fig. 1C,D), we strategically selected the tripeptide combination of fibronectin, collagen I and laminin-mimicking peptides at 1.1 kPa stiffness for subsequent experiments. The gene discussed is FN1; the disease is neoplasm.