In IPDF and BLM-induced IPF mouse lung fibroblasts (BLM-MLF), CSF3 knockdown reduced fibrosis marker expression and phospho-STAT3 levels, similar to the effects observed in CSF3 KO mice (Fig. 2j–l and Supplementary Fig. 4a–c). This evidence concerns the gene CSF3 and idiopathic pulmonary fibrosis.