A ketogenic diet, known to increase SCFA levels, has been proposed to counteract these effects by restoring the histone acetylation balance and modulating immune responses, potentially offering therapeutic benefits in MS and related conditions.175,176 Notably, infiltrating CD4+ T cells in the CSF of MS patients cross-react with gut microbial peptides from MS-associated bacterial genera that have high homology with human peptides, suggesting a role for the gut microbiota in MS pathogenesis.177. The gene discussed is CD4; the disease is myeloid sarcoma.