Richards et al.23reported an individual with a de novo ∼400 kb deletion overlapping MAD1L1 (MIM: 602686), MRM2 (MIM: 606906), NUDT1 (MIM: 600312), SNX8, and the first exon of EIF3B. This individual presented with TOF, language delay, facial dysmorphisms, and failure to thrive.23 This evidence concerns the gene EIF3B and Failure to thrive.