,23,24,25,26,27,28 Regarding EIF3A, a missense variant, c.1145A>G (GenBank: NM_003750.4) (p.Tyr382Cys), was found to segregate with left-ventricular noncompaction (LVNC) in two related individuals.29 This evidence concerns the gene EIF3A and left ventricular noncompaction.