INPP4A and asthma: INPP4A was further shown to dampen airway inflammation and alleviate asthma in mice [271], with a single nucleotide polymorphism (SNP) in INPP4 correlating with asthma susceptibility in patients [272], which has been contributed to an INPP4-mediated reduction in oxidative stress-induced PI(3,4)P2 accumulation [273].