For reference, Gardiwal et al. 19 reported that MLPKO relative to healthy MLP+/+ controls had significant prolongations of RR (10 ms), QRS (4 ms), QT (21 ms), QTc (19 ms), and JT (17 ms).19,36 Consistent with previously published finding that in healthy mice cRadKO reduces QTc,10 in DCM rescue, cRADΔ/Δ-MLPKO also enhances repolarization. This evidence concerns the gene CSRP3 and familial dilated cardiomyopathy.