Interestingly, despite their marked differences in basal catalytic activity (as assessed by autopalmitoylation), wt and all XLID forms of ZDHHC9 appear to show enhanced activity (measured by both auto- and MBP palmitoylation) in the presence of Golga7, suggesting that the association with Golga7 (which also localizes to Golgi outposts) is central to ZDHHC9 activity. Here, MBP is linked to cask-related x-linked intellectual disability.