Interestingly, the XLID mutant ZDHHC9-P150S still palmitoylates MBP in a Golga7-dependent manner in transfected non-neuronal cells, raising the possibility that impaired subcellular localization in OLs, rather than impaired catalytic activity, may cause or contribute to WM abnormalities in some cases of ZDHHC9-associated XLID. This evidence concerns the gene MBP and cask-related x-linked intellectual disability.