TRPM3 and hypertensive disorder: To establish a possible correlation between TRPM3 expression levels in the kidney and BP, we also measured TRPM3 mRNA expression in a well-recognized model of hypertension, normotensive (BPN, BP normal) and hypertensive (BPH, BP high) mouse strains.17,18 Interestingly, mRNA expression levels of TRPM3 in kidney were significantly higher in BPH compared with BPN mice (Figure S3).