MTOR and Alzheimer disease: However, analysis of mTOR S2448 phosphorylation showed a significant two‐way interaction (Figure 1B; interaction, F[1, 29] = 7.766, p = 0.0093), whereby female controls had significantly higher mTOR S2448 phosphorylation than control males (Figure 1B; pmTOR‐S2448 = 0.0155) and AD males has significantly higher mTOR s2448 phosphorylation compared to control males (Figure 1B; pmTOR‐S2448 = 0.0363).