Several circulating lncRNAs, including metastasis-associated lung adenocarcinoma transcript 1 (MALAT1), urothelial carcinoma-associated 1 (UCA1), HOX transcript antisense RNA (HOTAIR), cytoskeleton regulator RNA (CYTOR), and growth arrest-specific transcript 5 (GAS5), have demonstrated significant biomarker potential in breast cancer and other malignancies [22–26]. The gene discussed is CYTOR; the disease is breast cancer.