While proteins with higher activity in poor responders showed enrichments in “04151_PI3K-Akt signaling pathway”, “04621_NOD-like receptor signaling pathway”, “04620_Toll-like receptor signaling pathway”, “05131_Shigellosis”, “05162_Measles” and “[R-HSA-1643685] Disease” (see Supplementary Table S9). Here, AKT1 is linked to shigellosis.