CYP19A1 and neoplasm: Regarding the limitations of current GC diagnostic methods (such as gastroscopy and tumor marker detection) in terms of sensitivity and specificity, this study identified five ADME-related prognostic genes (UGT1A1, ADH4, ADH1B, CYP19A1, and GPX3) that exhibit unique expression patterns in tumor tissues (UGT1A1, ADH1B, CYP19A1, and GPX3 show significant downregulation).