NR2F2, a ligand-inducible nuclear receptor of the steroid/thyroid hormone receptor superfamily, is mechanistically linked to colorectal cancer progression through its role in TGF-β-dependent EMT, a process critical for tumor cell invasion, metastasis, and poor clinical outcomes (Wang et al., 2015; Wang et al., 2017). Here, TGFB1 is linked to neoplasm.