Notably, the association between nonparaneoplastic cerebellar ataxia and CASPR2 antibodies was first documented in 2012 (Becker et al., 2012), with cerebellar symptoms estimated to occur in approximately 14% of patients with anti-CASPR2 antibodies (Boyko et al., 2020). The gene discussed is CNTNAP2; the disease is cerebellar ataxia.