Categorizing apoB, LDL-C, and TyG indices according to tertiles, higher levels of ApoB were significantly associated with the severity of coronary artery stenosis in patients with acute myocardial infarction (P<0.001), whereas no such associations were found for elevated levels of LDL-C and TyG indices (P >0.05). Here, APOB is linked to acute myocardial infarction.