Alterations in gut microbiota conformation and its resultant metabolites may subsidize the development and progression of T2DM Intestinal microbiota‐derived metabolites like short‐chain fatty acids (SCFAs) could control insulin sensitivity and inflammation; the metabolites can be profiled by means of foodomics policies (Hosomi et al. 2022). This evidence concerns the gene INS and type 2 diabetes mellitus.