A total of 470 bone metastatic sites were documented among 100 newly diagnosed patients with prostate cancer with confirmed bone metastasis on technetium-99 bone scan investigation, aged 51 to 89 (mean age = 68.81, mode = 65, SD = 7.07 years), PSA (mean = 924.32, range = 5.76 to 2223, SD = 2656.47 ng/ml), and ALP (mean = 239.43, range = 45 to 3265, SD = 438.57). Here, KLK3 is linked to Familial prostate cancer.