On postoperative day 1, the patient experienced persistent hypertension, significant thrombocytopenia (12 x 10^9/L), coagulopathy, acute kidney injury (creatinine 141.4 umol/L), oliguria (24-hour urine output of 150 ml), hyperkalemia (6.03 mmol/L), and liver dysfunction (ALT: 371.3 U/L) (Table 1). Continuous renal replacement therapy (CRRT) was initiated. By the third postoperative day, despite CRRT, the patient's creatinine levels continued to rise, accompanied by thrombocytopenia, a negative Coombs test, hemolysis, and fragmented RBCs (4%). This evidence concerns the gene GPT and Thrombocytopenia.