Professor Cui performed bioinformatics analysis of common differentially expressed genes (cDEG), fasting differential genes (fDEGs), and mitochondria-related genes, validated the overlapping genes identified by RT-qPCR and Western blotting in various mouse models of sarcopenia, and identified three hub genes (Acss1, Mtfp1, and Oxct1), which are closely associated with mitochondrial dysfunction in sarcopenia (Cui et al., 2024), See Figure 6D. The gene discussed is MTFP1; the disease is sarcopenia.