In a study on calcium oxalate (CaOx) kidney stones, it is speculated that CaOx promotes kidney stone formation by downregulating the Cav-1 and low density lipoprotein receptro-related protein 6 (LRP6)/Wnt/β-catenin pathways, causing autophagy dependent ferroptosis (82). Here, CAV1 is linked to nephrolithiasis.