The highly expressed circRNA BIRC 6 (circBIRC 6) in gastric cancer (GC) patients can increase Cav-1 expression by regulating the miR-488-glutamate ionotropic receptor N-methyl-D-aspartate type subunit 2D (GRIN2D) axis, thereby inhibiting autophagy and promoting GC progression (58). This evidence concerns the gene CAV1 and gastric cancer.