The abnormal expression of Cav-1 and dysfunction of Caveolae are closely related to various diseases, including fatty liver disease (12), muscular dystrophy (2), infection (13), osteoporosis (14), cancer (15), cardiovascular disease (16), neurological disease (17), etc. For example, high expression of Cav-1 affects the prognosis of breast cancer patients (18). The gene discussed is CAV1; the disease is osteoporosis.