Endoglin is widely involved in the regulation of inflammation in various immune diseases, including rheumatic diseases, hereditary hemorrhagic telangiectasia-1 (HHT-1), and preeclampsia (Venkatesha et al., 2006; Mangoni and Zinellu, 2024; Hawinkels et al., 2010; Rossi et al., 2016). Here, ENG is linked to telangiectasia, hereditary hemorrhagic, type 1.