Insulin resistance from muscle damage is associated with decreases in GLUT4 content and gene transcription, as well as impairments in insulin signaling (Asp, Daugaard, & Richter, 1995; Asp, Kristiansen, & Richter, 1995; Del Aguila et al., 2000; Kristiansen et al., 1997). The gene discussed is INS; the disease is Insulin resistance.