Several genes previously reported as subgroup-specific drivers or tumor lineage markers, such as PTCH1, PDE1C, and ST18 in SHH [9, 49] and OTX2, EOMS, and LMX1A in G3 [9, 57], were recovered and detected as DEGs exclusively in GNP and RL, respectively. This evidence concerns the gene OTX2 and neoplasm.