However, it is important to note that petBrain can run without amyloid-PET to provide only T2 and N, or without tau-PET to provide only A and N. In addition, although petBrain provides regional tauopathy progression data by extracting SUVr values from 122 predefined gray matter regions of interest, it currently lacks simplified, clinician-oriented outputs. Here, MAPT is linked to tauopathy.