Additionally, respondents who reported having their first sexual encounter before the age of 18 (mean GAD score = 3.22, p < 0.001; mean PHQ score = 3.45, p < 0.001) or their first birth before the age of 18 (mean GAD score = 3.31, p < 0.001; mean PHQ score = 3.53, p < 0.001) exhibited significantly greater symptoms of both anxiety and depression. This evidence concerns the gene GAD1 and major depressive disorder.