Furthermore, Luminex analysis in supernatants of DUSP8-GFP, sh-DUSP8-GFP and their relative GFP-control GSC#1 and GdEC#1 transduced cells revealed that DUSP8 modulation exerts opposite effects in a group of four secreted molecules, all implicated in the malignant behaviour of GBM. Here, DUSP8 is linked to glioblastoma.