Among the transcripts down-regulated in DUSP8-GFP GSC#1 and up-regulated in sh-DUSP8-GFP GSC#1 we found stanniocalcin-1 (STC1), a secreted glycoprotein associated with poor prognosis, glioma grade, and resistance to TMZ therapy [33]. This evidence concerns the gene STC1 and central nervous system cancer.