PECAM1 and brain neoplasm: Moreover, MVD analysis of brain tumors showed that microvessel counts (using CD31 staining) in sh-DUSP8-GFP (0.051 ± 0.01, mean ± SD), were significantly higher respect to either GFP (0.067 ± 0.006, mean ± SD), and DUSP8-GFP tumors (0.00026 ± 0.00042, mean ± SD) (Supplementary Fig. S9C).