Recent studies have demonstrated that BMP signaling participates in regulating endothelial cell function in various pulmonary diseases, including pulmonary fibrosis and pulmonary arterial hypertension.[49, 50] Furthermore, through detailed investigation, we found that PARK7 regulates BMP2/4 and BMPR1A/B through distinct mechanisms: it modulates BMP2/4 transcription via NRF2, a key interacting partner, while it regulates BMPR1A/B mRNA stability through the expression and binding activity of the RNA‐binding protein HuR. The gene discussed is NFE2L2; the disease is pulmonary arterial hypertension.