PARK7/DJ‐1, a Parkinson's disease‐associated protein, exhibits antioxidative properties in multiple pathological conditions, including ALI, and interacts with critical signaling molecules such as Akt and NRF2 that regulate essential biological processes.[24, 25, 26, 27] PARK7 negatively regulates ferroptosis by modulating GSH biosynthesis.[48] Through genetic knockout and overexpression approaches, we investigated the relationship between PARK7 and FADS1/2. This evidence concerns the gene NFE2L2 and Parkinson disease.