In mesenchymal gastric cancer cells, the upregulation of FADS1 expression leads to sensitization to ferroptosis.[21] The dual FADS1/2 inhibitor CP‐24879 exhibits anti‐inflammatory effects in a mouse mastocytoma model.[41] Studies on viral hepatitis have shown that increased expression of FADS2 enhances ferroptosis sensitivity and increases susceptibility to antiviral drugs.[42] The existence of such contradictions is understandable. Here, FADS1 is linked to gastric cancer.