We treated mesenchymal highly-metastatic HEY A8, mesenchymal less-metastatic HEY, and epithelial least-metastatic OVCAR3 ovarian cancer cell lines with 10 μM of the small molecule chemical drug BAY1125976 for 24 h to induce AKT2 inhibition16 followed by AFM measurement of the cell viscous properties. The gene discussed is AKT2; the disease is ovarian carcinoma.