Next, we included genes that are: (1) implicated in the pathogenesis of cGN; (2) essential for pathways involved in leukocyte infiltration and activation; (3) associated with cytokine and chemokine signaling and inflammation from the Kyoto Encyclopedia of Genes and Genomes15, Reactome16 and Gene Ontology17 databases; and (4) differentially expressed between normal and inflamed glomerular regions, based on our recently published spatial transcriptomics data from patients with ANCA-GN and controls18. The gene discussed is CGN; the disease is ganglioneuroma.