Recently, members of this research group observed a substantial rise in the number and heterogeneity of neutrophils in sepsis, indicating an increased production and release of immature granulocytes into the bloodstream during emergency granulopoiesis, which was significantly enriched in patients with the SRS1 subtype27, with evidence of expansion of immature neutrophil populations (notably IL1R2+ cells) and immunosuppressive effects on T cells in vitro27. This evidence concerns the gene IL1R2 and Sepsis.