CRP and chronic obstructive pulmonary disease: Yao et al. evaluated the predictive capacity of NLR, platelet-to-lymphocyte ratio (PLR), and C-reactive protein (CRP) for in-hospital mortality in patients with acute exacerbation of chronic obstructive pulmonary disease, finding that NLR outperformed PLR and CRP, with sensitivity and specificity of 81.08% and 69.17%, respectively48.