ATXN2 and hydrops fetalis: Subsequent analyses utilizing Hypothesis Prioritisation in Multi-trait Colocalization (HyPrColoc)30 revealed robust colocalization evidence for this locus between LTL and all CVDs, excluding AF, HF and PAD, with a posterior probability (PP) higher than 0.7, which encompassed the shared causal SNP (rs10774625, an intronic variant of the ataxin 2 (ATXN2) gene on 12q24.12) (Supplementary Data 19).