TFE3 and renal cell carcinoma associated with Xp11.2 translocations/TFE3 gene fusions: The MiT family tRCC is characterized by chromosomal rearrangements that fuse the transcription factor E3 (TFE3) or EB (TFEB) (on chromosomal loci Xp11.2 and 6p21, respectively) with various partners6–10.