A protective trend was also observed against malaria diagnosed via qPCR for anti-CSP IgG3 (C-1 and D11–D13), whereas anti-DBLα IgG4 (D11–D13) and anti-RH1 IgG3 (C-1, D7, D11–D13) were associated with risk of qPCR positivity. The gene discussed is DNAJC5; the disease is malaria.