TERT and neoplasm: This resulted in telomere-dependent TERT transcription in multiple cell types/models as in: (a) short/long telomere HT1080, HCT116, MDA-MB-231 cells, and primary FS fibroblast along with corresponding derived iPSC; (b) temporal TL elongation with subsequent shortening; (c) TL-dependent transcription from artificially inserted TERT promoter; (d) and, tumour cells grown in vivo in mice.