Experimental animal studies have shown that intracranial aneurysm formation, progression, and rupture could be mitigated by inhibiting SASP factors such as IL‐1β, TNF‐α, MCP‐1, and MMPs (Moriwaki et al. 2006; Starke et al. 2014; Aoki et al. 2007, 2009). The gene discussed is IL1B; the disease is Dilatation of the cerebral artery.