ALK and familial pancreatic carcinoma: For NVP‐TAE684, this anaplastic lymphoma kinase (ALK) inhibitor, a subfamily of tyrosine kinase inhibitors, is able to induce G2/M phase cell cycle arrest and apoptotic cell death across multiple pancreatic cancer cell lines, particularly the fast‐growing COLO‐357, which is also a known function of topoisomerase II inhibitors and blocks MYC's promotions of the cell cycle [44, 45].