SERPINA1 and metabolic dysfunction-associated steatotic liver disease: The majority of HCC cases manifest in patients with underlying liver pathologies, often associated with chronic viral hepatitis caused by viruses such as hepatitis B or C, chronic alcohol use, acquired or hereditary metabolic disorders such as nonalcoholic fatty liver disease (NAFLD), and genetic conditions such as hemochromatosis or alpha-1-antitrypsin deficiency [4, 5].