Specific human leukocyte antigen (HLA) haplotypes have been linked with DRESS syndrome and drugs: HLA-B*5701 (abacavir), HLA-DR3, HLA-DQ2, HLA-A*3101 (carbamazepine), and HLA-B*5801 (allopurinol) [7]. Here, PPIB is linked to drug hypersensitivity syndrome.