First, due to sampling and hardware constraints, we could not extract the CCNE1(+) Cells for research; second, in terms of immune escape from this population of cells, some other immune checkpoints showed higher expression in the CCNE1(+) Cells in lymph nodes, which may influence future tumor progression; additionally, marker genes with higher tumor intrinsic expression in CCNE1(+) Cells may also promote metastasis, necessitating further verification. Here, CCNE1 is linked to neoplasm.