As we have previously seen that, expressions of both CASC19 and PSPC1 were high in pancreatic cancer cell line MIAPaCa-2 than normal pancreatic cell line HPNE, we compared the amount ubiquitinated PSPC1 in both the cell lines and have found that ubiquitination of PSPC1 was remarkably less in MIAPaCa-2 cells which has high endogenous CASC19 expression. Here, PSPC1 is linked to familial pancreatic carcinoma.