Paraspeckle component protein PSPC1 is found to be upregulated in breast cancer, lung cancer, nasopharyngeal cancer and hepatocellular carcinoma along with pancreatic cancer (Zhan et al. 2023; He et al. 2021; Takeiwa et al. 2022; Yuan et al. 2024). This evidence concerns the gene PSPC1 and familial pancreatic carcinoma.