CASC19 (Cancer susceptibility candidate 19) was one such lncRNA which caught our attention as it was found to be deregulated in several other cancer types (Liu et al. 2020, 2021; Qu et al. 2019; Wang et al. 2019a, b, 2020, 2023a, b, c; Zhao et al. 2019) and encoded by chromosomal locus 8q24.21, a “gene desert” and mutational hotspot region, linked to numerous cancer phenotypes (Wilson and Kanhere 2021). This evidence concerns the gene CASC19 and cancer.